Nkhani

Peptide yamkuwa imatchedwansoGHK-kundi zovuta zopangidwa ndi kuphatikiza kwakatatu - 1ndi copper ion.Deta ya kafukufuku ikuwonetsa kuti mkuwa m'thupi la nyama umagwira ntchito yofunika m'njira zosiyanasiyana, makamaka chifukwa cha kukopa kwa mkuwa pa ma enzymes a antioxidant.Pali michere yambiri yofunika mthupi la munthu komanso khungu yomwe imafunikira ayoni amkuwa.Ma enzymes awa amagwira ntchito pakupanga minofu yolumikizana, anti-oxidation ndi kupuma kwa cell.Mkuwa umagwiranso ntchito yowonetsera, yomwe ingakhudze khalidwe ndi kagayidwe ka maselo.Copper peptide ikasungunuka m'madzi, imawonetsa mtundu wabuluu wachifumu womwe umatchedwanso Blue Copper peptide m'mafakitale.

Kafukufuku akuwonetsa kuti Copper peptide ili ndi mapindu ambiri pakusamalira khungu, yomwe imatha kugwiritsidwa ntchito kwambiri m'makampani azodzikongoletsera.

1. Ntchito ya peptide yamkuwa pakukonzanso khungu

Kafukufuku akuwonetsa kuti peptide yamkuwa imasinthira ma metalloproteinase osiyanasiyana pomanganso khungu la makoswe.Ntchito ya enzyme imalimbikitsa kuwonongeka kwa mapuloteni a extracellular matrix, omwe amatha kuwongolera kuwonongeka kwa mapuloteni a extracellular matrix (mapuloteni a ECM) ndikuteteza kuwonongeka kwakukulu kwa khungu.Peptide yamkuwa imawonjezera core proteoglycan.Ntchito ya proteoglycan iyi ndikuletsa kupangika kwa zipsera ndikuchepetsa kuchuluka kwa kusintha kwa kukula kwa chinthu (TGF beta), komwe kumawonjezera zipsera powongolera kusonkhana kwa ma collagen fibrils.

2. Imalimbikitsa kaphatikizidwe ka collagen

Zoyesera zambiri zatsimikizira kuti tripeptide-1 imathandizira kaphatikizidwe ka collagen, kusankha glycosaminoglycan ndi mapuloteni ang'onoang'ono a glycan deproteinization.Kuphatikiza apo, imathanso kuwongolera kaphatikizidwe ka metalloproteinase.Ena mwa ma enzymes amathandizira kuwonongeka kwa mapuloteni a extracellular matrix, pomwe ena amatha kuletsa ntchito ya protease.Izi zikuwonetsa kuti peptide yamkuwa imatha kuwongolera kuchuluka kwa mapuloteni pakhungu.

3. Anti-inflammatory ndi antioxidant

Zinapezeka kuti peptide yamkuwa imalepheretsa kutupa mwa kuchepetsa milingo ya cytokines yotupa monga TGF-beta ndi TNF-a mu gawo lalikulu.Tripeptide-1 imachepetsanso kuwonongeka kwa okosijeni mwa kuwongolera kuchuluka kwachitsulo ndikuzimitsa zinthu zapoizoni zamafuta acid lipid peroxidation.

4. Limbikitsani kuchira kwa mabala

Kafukufuku wambiri wa nyama atsimikizira kuti peptide yamkuwa ya buluu imatha kuchiritsa mabala.Mu kuyesa kwa kalulu, peptide yamkuwa ya buluu imatha kufulumizitsa machiritso a bala, kulimbikitsa angiogenesis, ndikuwonjezera zomwe zili m'magazi a antioxidant michere.

5. Bwezerani ntchito ya maselo owonongeka

Fibroblasts ndi maselo akuluakulu a machiritso a bala ndi kusinthika kwa minofu.Sikuti amangopanga zigawo zingapo za matrix owonjezera, komanso amatulutsa zinthu zambiri zakukulira.Kafukufuku mu 2005 adawonetsa kuti tripeptide-1 imatha kubwezeretsanso mphamvu ya ma fibroblasts otenthedwa.

Peptide yamkuwa ndi mtundu wa polypeptide wokhala ndi anti-kukalamba komanso kukonza zinthu.Sizingatheke kulimbikitsa kupanga mtundu wa I, IV ndi VII collagen, komanso kulimbikitsa ntchito ya collagen synthesis cell fibroblast, yomwe ndi yopambana kwambiri yotsutsa kukalamba.

Pankhani ya kukonzanso, peptide yamkuwa imatha kuteteza ma fibroblasts omwe amalimbikitsidwa ndi UV, kupititsa patsogolo ntchito zawo, kuchepetsa kutulutsa kwa MMP-1, kuthana bwino ndi zinthu zotupa zomwe zimapangidwa ndi kukhudzidwa, kusunga khungu lotchinga ntchito lowonongeka chifukwa cha zokopa zakunja, ndipo ali ndi anti anti. matupi awo sagwirizana ndi kuchepetsa mphamvu.Peptide yamkuwa imaphatikiza zotsutsana ndi ukalamba ndi kukonza, zomwe ndizosowa kwambiri pazinthu zamakono zotsutsana ndi ukalamba ndi kukonza.