Amphotericin B 1397-89-3 Antibiotic
Malipiro:T/T, L/C
Koyambira:China
Port Yotumizira:Beijing / Shanghai / Hangzhou
Mphamvu zopanga:100kg / mwezi
Order(MOQ):25kg pa
Nthawi yotsogolera:3 Masiku Ogwira Ntchito
Malo osungira:ndi chikwama cha ayezi choyendera.Sungani pa 2-8 ℃ kwa nthawi yayitali.
Zamkatimu:ng'oma
Kukula kwa phukusi:25kg / ng'oma
Zambiri zachitetezo:Osati zinthu zoopsa
Mawu Oyamba
Amphotericin B, imatha kutchedwa Fungizone kapena Ambisome, yomwe ndi mankhwala oletsa tizilombo toyambitsa matenda a polyene omwe ali olekanitsidwa ndi chikhalidwe cha Streptomycesnodosus.Imalekanitsidwa ndi magawo awiri okhala ndi A ndi B, koma gawo la A siligwira ntchito pang'onopang'ono kwa antifungal omwe sagwiritsidwa ntchito, kotero anthu amagwiritsa ntchito gawo B lokha lomwe limatchedwa Amphotericin B.
Ndi mankhwala a antifungal omwe amagwiritsidwa ntchito pa matenda oopsa a fungal ndi leishmaniasis.Lili ndi ntchito ziwiri zosiyana pogwiritsa ntchito pakamwa ndi jekeseni.
Amphotericin B ndiye chisankho choyamba cha matenda oyamba ndi fungus chifukwa ali ndi antifungal spectrum.Iwo ali ziletsa ntchito kwa mafangasi monga cryptococcus, coccidium, candida albicans ndi blastomycetes, etc. Adzapha fugal pa mkulu ndende, amene ndi othandiza mankhwala zochizira matenda bowa kwambiri.
Waukulu chipatala zizindikiro monga: 1. Chithandizo cha mafangasi monga cryptococcosis, North America blastomycosis, kufalitsidwa candidiasis, coccidiosis ndi histoplasmosis.2. Chithandizo cha mucormycosis chifukwa ena mafangasi ngati Rhizopus, colporium, endomycetes ndi chule ndowe nkhungu.3. Chithandizo cha sporotrichosis chifukwa cha sporotrichosis schenckii.4. Chithandizo cha aspergillosis chifukwa cha Aspergillus fumigatus.5. Zokonzekera zam'mutu ndizoyenera kwa mycosis ya pigmented.Ndiwoyeneranso pakhungu matenda mafangasi pambuyo amayaka, kupuma thirakiti Candida ndi Aspergillus kapena cryptococcus matenda, komanso ntchito mafangasi cornea chilonda.
Zotsatira zoyipa zomwe zimachitika nthawi zonse zimaphatikizansopo kutentha thupi, kuzizira, ndi mutu mutangolandira mankhwala, komanso mavuto a impso.Zizindikiro zosagwirizana ndi anaphylaxis zimatha kuchitika.Zotsatira zina zowopsa zimaphatikizapo kuchepa kwa potaziyamu m'magazi ndi kutupa kwa mtima.Zikuoneka kuti zimakhala zotetezeka panthawi yomwe ali ndi pakati.Pali mapangidwe a lipid omwe ali ndi chiopsezo chochepa cha zotsatirapo zake.Ili m'gulu la mankhwala a polyene ndipo imagwira ntchito pang'onopang'ono posokoneza nembanemba ya cell ya bowa.Iyenera kugwiritsidwa ntchito mosamala pakachitika zinthu, chifukwa chitetezo chiyenera kutsatira malangizo achipatala.
Matchulidwe Oral Grade (In House Standard)
| Kanthu | Kufotokozera |
| Maonekedwe | Ufa wachikasu mpaka lalanje-wachikasu, wopanda fungo kapena pafupifupi wopanda fungo. |
| Chizindikiritso | IR, HPLC |
| pH | 4.0-6.0 |
| Kutaya pa Kuyanika | ≤5.0% |
| Phulusa la Sulfated | ≤3.0% |
| Zogwirizana nazo | ≤0.5% |
| 303nm pa | Chidetso A (Amphotericin A) ≤5.0% Chidetso chosadziwika chamunthu ≤1.0% |
| 383nm pa | Chidetso B (Amphotericin X1) ≤4.0% Chidetso chosadziwika chamunthu ≤2.0% |
| Zonse Zonyansa | ≤15.0% |
| Zotsalira zosungunulira | Methanol ≤0.3% Acetone ≤0.5% |
| Kuyesa | ≥850 amphotericin B mayunitsi/mg pa zinthu zouma. |
Matchulidwe Oral Grade (In House Standard)
| Kanthu | Kufotokozera |
| Maonekedwe | Yellow mpaka lalanje ufa wopanda fungo. |
| Chizindikiritso | IR, HPLC |
| Zotsalira pakuyatsa | ≤0.5% |
| Zogwirizana nazo |
|
| ku 303nm | Amphotericin A ≤2.0% |
| Chidetso chosadziwika chamunthu ≤1.0% | |
| ku 383nm | Amphotericin X1 ≤4.0% |
| Chidetso chosadziwika chamunthu ≤2.0% | |
| Zonyansa zonse | ≤15.0% |
| Zotsalira zosungunulira | Acetone ≤0.5% |
| Methanol ≤0.3% | |
| Malire a Microbiological | Aerobic microbial count ≤1000cfu/g |
| Nkhungu & yisiti ≤100cfu/g | |
| Escherichia coli palibe mu 1 g | |
| Bakiteriya endotoxins | <1.0EU/mg |
| Kuyesa | ≥850 amphotericin B mayunitsi/mg, owerengedwa pa maziko zouma |
