Zogulitsa

Alprostadil, wotchedwanso Prostaglandin E1 kapena PEG1.Ambiri alipo mu thupi la biologically yogwira zinthu, monga mmodzi wa prostaglandin banja, ndi anazindikira amkati physiologically yogwira mankhwala.

Itha kugwiritsidwa ntchito mwachindunji pamitsempha yosalala ya mitsempha, kukulitsa mitsempha yamagazi ndikuwonjezera kutuluka kwa magazi, zomwe zimatha kusintha ma microcirculation perfusion.Ikhoza kulepheretsa kuphatikizika kwa mapulateleti ndi kupanga thromboxane A2, komanso kulepheretsa atherosclerosis, lipid plaque ndi mapangidwe a chitetezo cha mthupi.

Lilinso ndi zotsatira zotsatirazi: kukulitsa kwa periphery mitsempha yaing'ono yamagazi ndi mitsempha ya m'mitsempha, kuchepetsa zotumphukira mtima kukana ndi kuthamanga kwa magazi.Kuteteza mapulateleti omwe amatha ku thrombosis.Kuteteza ischemic myocardium, yomwe imatha kuchepetsa kukula kwa myocardial infarct.Amagwiritsidwanso ntchito pochiza kulephera kwa mtima.Imakhala ndi diuretic ndi aimpso kuteteza ntchito, kutengera kukula kwa mitsempha yaimpso kuti iwonjezere magazi a aimpso.Mwanjira imeneyi, imatha kuchotsa nayitrogeni yopanda mapuloteni, ndikuwongolera bwino kwa sodium ndi madzi.

Ndi matenda ntchito ambiri.Monga zovuta za matenda a shuga, matenda amtima komanso kulephera kwamtima kosatheka.Komanso kugwiritsidwa ntchito pazochitika monga matenda a mtima obadwa nawo omwe amaphatikizidwa ndi pulmonary hypertension, cerebral infarction ndi matenda osatha a arterial occlusive disease.Nthawi zina monga kugontha mwadzidzidzi, kutsekeka kwa retinal mtsempha, matenda a chiwindi a virus kapena gastritis yosatha, imakhalanso ndi ntchito.Angagwiritsidwe ntchito kuchipatala pa matenda ena monga duodenal chilonda, aakulu aimpso insufficiency ndi kapamba.Amagwiritsidwa ntchito poika ziwalo.Amagwiritsidwa ntchito pa matenda ena monga erectile dysfunction, induction labor and postpartum hemorrhage, femoral head necrosis, lumbar disc herniation, postherpetic neuralgia ndi mphumu ya bronchial.

Iyenera kuchenjezedwa kwa odwala omwe ali ndi matenda monga mtima kulephera, glaucoma, chilonda cham'mimba kapena chibayo chapakati.Ndi imakwiyitsa kwambiri mtsempha, adzasonyeza zizindikiro za kutupa monga redness, kutupa, kutentha ndi ululu, amene angayambitse phlebitis.Iyenera kuyimitsidwa kuti igwiritsidwe ntchito pachitetezo zikachitika.